Nature, Published online: 07 April 2026; doi:10.1038/d41586-026-01024-7A burgeoning field is launching its first clinical trial to find out whether dialling back cell development c... Read more Nature, Published online: 07 April 2026; doi:10.1038/d41586-026-01024-7A burgeoning field is launching its first clinical trial to find out whether dialling back cell development can safely refresh aged tissues and organs. Show less

Nature Climate Change, Published online: 07 April 2026; doi:10.1038/s41558-026-02602-3Meeting global temperature targets requires deep mitigation across sectors. Moving away from c... Read more Nature Climate Change, Published online: 07 April 2026; doi:10.1038/s41558-026-02602-3Meeting global temperature targets requires deep mitigation across sectors. Moving away from cost optimality when allocating mitigation by sector, the authors link integrated assessment models and portfolio analysis to identify and balance trade-offs between Sustainable Development Goal indicators. Show less

Latest scorecard from the Indian Premier League match between Rajasthan Royals and Mumbai Indians in Guwahati.

Nature, Published online: 07 April 2026; doi:10.1038/d41586-026-01125-3Nature correspondent Alexandra Witze takes over Nature Briefing for a special edition from mission control in... Read more Nature, Published online: 07 April 2026; doi:10.1038/d41586-026-01125-3Nature correspondent Alexandra Witze takes over Nature Briefing for a special edition from mission control in Houston. Show less

A Bradford school has been rated Outstanding in all areas in a report.

Nature Genetics, Published online: 07 April 2026; doi:10.1038/s41588-026-02561-7A series of in vitro and in vivo CRISPR activation screens combined with in situ Perturb-seq identif... Read more Nature Genetics, Published online: 07 April 2026; doi:10.1038/s41588-026-02561-7A series of in vitro and in vivo CRISPR activation screens combined with in situ Perturb-seq identify regulators of T cell-dependent cytotoxicity in melanoma. Show less

Anthropic added $10b in revenue in the last month alone, twice Databricks’ annual run rate. Crossing $10b is a milestone few software companies ever reach: ServiceNow took 20 years, Shopify took 18... Read more Anthropic added $10b in revenue in the last month alone, twice Databricks’ annual run rate. Crossing $10b is a milestone few software companies ever reach: ServiceNow took 20 years, Shopify took 18, Palo Alto Networks took 19, & Anthropic crossed that threshold in under four years. But who’s looking backwards? How long until Anthropic is the most valuable company in the world? NVIDIA generates $215b in annual revenue & trades at 22x, producing a $4.8 trillion market cap. To surpass it, Anthropic needs $200b in annual revenue1. If growth continues, three years. If it decelerates steadily, four. If it normalizes rapidly, seven2. The usual caveat applies: significant customer concentration. ServiceNow needed two decades to reach $10b. Anthropic needed forty-two months; then added another Databricks in thirty days. Assuming a 25x forward revenue multiple, compared to NVIDIA’s 22x on its $215b run rate producing a $4.8 trillion market cap. ↩︎ Bull case assumes 150% growth in year one, declining to 100%, 50%, then 25%. Base case assumes 100% growth declining to 67%, 50%, then 33%. Bear case assumes 50% growth declining to 40%, 30%, then 25%. ↩︎ Show less

Nature, Published online: 07 April 2026; doi:10.1038/d41586-026-01016-7Mutations in the KRAS protein were once deemed ‘undruggable’. Today, various approaches are in the pipeline.

Defense Secretary Pete Hegseth says US forces are carrying out more strikes on Iran than any day since start of war.

BC Wildfire crews are en route